Welcome to WeFold, a large-scale online coopetition project devoted to advancing the protein folding problem.WeFold is a byproduct of CASP. CASP (Critical Assessment of techniques for protein Structure Prediction) is a community-wide, worldwide experiment for protein structure prediction that takes place every other year and challenges computational scientists to predict the 3D structure of newly, or soon to be determined, but yet unpublished proteins given their primary sequence of amino acids.This site is a science community gateway designed to bring together labs and individuals for online discussion, sharing, and collaboration during CASP11. We invite young and more seasoned scientists as well as citizen scientists in general to participate in this collaborative project.This year the WeFold project is structured into 4 main forums with different levels of access:

CASP Experiment Forum. This forum is similar to the one in the first WeFold experiment. It enables the interaction among groups that contribute different components of the protein structure prediction pipeline. The goal is to leverage expertise at a scale that would be hard to achieve otherwise. See the list of participants here.

Open CASP Forum. This forum is for discussion of ideas about protein structure prediction methods. This is an open forum and it does not involve CASP participation. The goal is to bring new ideas to the virtual table and to test them when they become mature for CASP.

Machine Learning Forum. This forum is for machine learning experts to discuss the protein scoring problem. The goal is to engage the ML community to help the protein structure prediction community to solve the difficult problem of selecting the best computationally generated protein models out of the hundreds of thousands or even millions that the protein structure prediction methods can generate per protein.

Educational Forum. This forum is for those students that are directly involved in the WeFold activities as well as for those that are interested in learning about protein structure prediction. The goal is to get students excited about science by participating in the discussions pertaining the solution of one of the outstanding problem in modern science.

If you are interested in participating in any of these forums, please go to the Forums page.



Visit our archives to find information about our previous CASP experiments and to download the datasets that resulted from them.


Enter to the forums to discuss and contribute to the current CASP experiment.


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